Do Weight Loss Injections Really Work?

Do Weight Loss Injections Really Work?

The UK press recently announced that high street chemists have been given approval to sell Wegovy, the controversial weight loss injection. This follows reports in 2022 of the ‘game-changing weight loss injection‘ to be offered on the NHS. It seems too good to be true. Could a simple injection be all you need to get your weight challenges under control?

Our weight loss clinic has been inundated with calls from people asking if we offer “diet injections” or the “skinny jab”. No doubt as a result of extensive media coverage. Newspapers and magazines have reported that celebrities like Elon Musk and Kim Kardashian have lost weight using Ozempic, the same drug as Wegovy. Weight loss jabs like Ozempic have truly taken the world by storm.

So do weight loss injections really work? And should you consider getting one? Here’s what you need to know about the weight loss jabs everyone’s talking about.

If you’d like to find out how we can help you overcome your weight challenges naturally, achieve your desired weight and maintain it long term, we invite you to book a complimentary call with a member of our team to learn more.


Let’s start by looking at what’s actually in the syringe. Both of the most popular weight loss medications, Wegovy and Ozempic, are brand names for the drug Semaglutide. The difference between Wegovy and Ozempic is the dose. Wegovy is available up to 2.4mg whereas Ozempic is available up to 1mg.

Semaglutide is a medication originally used to treat type 2 diabetes. It belongs to a class of drugs called GLP-1 receptor agonists. These drugs work by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1) in the body.


Semaglutide works by increasing the release of insulin from the pancreas and reducing the amount of glucose produced by the liver. This helps to lower blood sugar levels in people with type 2 diabetes.

When it comes to losing weight, GLP-1 agonists can promote weight loss in a number of ways. One of the main ways is by reducing appetite. These drugs act on receptors in the brain that control hunger and satiety. This leads to an increased feeling of fullness and reduced appetite.

GLP-1 agonists also slow down the emptying of the stomach. This can help people feel fuller for longer after eating and reduce the urge to eat again soon after a meal.

Finally, GLP-1 agonists have been shown to boost the metabolism and increase energy expenditure.

There are currently five GLP-1 receptor agonists currently available in the UK according to NICE.


We have two primary concerns about this weight loss injection, both of which we’ll go on to discuss in more detail: Firstly, an injection alone does nothing to get to the root cause of why people have gained weight. Not tackling the root cause is highly likely to result in weight regain. Secondly, the list of potential side effects are concerning.


Not only do weight loss injections do little to ensure long term weight loss, they also come with some concerning side effects.

Common side effects listed on the Wegovy’s website include: nausea, diarrhea, vomiting, constipation, stomach pain, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, gas, stomach flu, heartburn.

So far, unpleasant, but not life threatening. However, we then come on to the more serious concerns. I have lifted the following text directly from Wegovy’s website:

Wegovy™ may cause serious side effects, including: Possible thyroid tumours, including cancer. Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rodents, Wegovy™ and medicines that work like Wegovy™ caused thyroid tumors, including thyroid cancer. It is not known if Wegovy™ will cause thyroid tumours or a type of thyroid cancer called medullary thyroid carcinoma in people.

A simple interpretation: rodents who were given these medications got cancer. You might too but we don’t actually know for sure. A full list of side effects can be found here.

Read our post on the side effects of weight loss injections here.

Recent research shows that around 30% of people discontinue taking the weight loss drugs Wegovy and Saxenda before reaching their target dose, potentially due to the side effects, with over half quitting within 12 weeks. Younger adults and those with higher barriers to care were least likely to adhere to the regimen.


If you’re willing to risk those sorts of side effects, you’d be hoping for a long term solution. Sadly though, the chances are you will regain weight after using these jabs. Especially if you don’t tackle the underlying issues that caused your weight gain in the first place.

GLP1 agonists like Ozempic, Wegovy and Saxenda have only having been made widely available for weight loss relatively recently. Despite this, there are already numerous reports of people regaining weight after coming off the drugs. Novo Nordisk are the makers of Wegovy and Ozempic. The company’s senior vice president of global drug discovery, Karin Conde-Knape, has said that people have to keep taking their drug to keep the weight off. CNBC reported that Conde-Knape said some individuals may actually gain more weight after stopping these drugs than they initially lost.

Individuals such as TikTok creator Remi Bader have spoken openly about their weight regain after using Ozempic. Remi claims that she “gained double the weight back” and shared that coming off the drug made her binge eating “so much worse”.


We have looked at the two most discussed weight loss injections, Wegovy and Ozempic, both of which contain the GLP-1 agonist Semaglutide. But what other weight loss injections are there?

Saxenda (liraglutide) is another GLP-1 medication and is FDA-approved for weight loss. Like Semaglutide, it works by reducing appetite and increasing feelings of fullness.

Contrave (naltrexone HCl and bupropion HCl) injections combine two medications that work to reduce appetite and cravings for food. Naltrexone was initially developed to treat addiction to opioids.

Qsymia (phentermine and topiramate) injections are also a combination of two medications. They work to reduce appetite and increase feelings of fullness. Phentermine is a stimulant and was withdrawn from the market in the UK in 2000. Qsymia can cause serious side effects including birth defects and suicidal thoughts and actions.

Belviq (lorcaserin) worked by affecting the serotonin receptors in the brain, which could reduce appetite and facilitate weight loss. In February 2020, the FDA requested that the manufacturer of lorcaserin withdraw the drug from the US market because a clinical trial showed an increased occurrence of cancer.


Ozempic and Wegovy both contain the drug Semaglutide, which is a synthetic version of a hormone called GLP-1. These are the two jabs being widely discussed in the press at present.

The difference between the two is the dosage amounts. Ozempic is available in doses of 0.25mg, 0.5mg, and 1mg, while Wegovy is available in higher doses. As well as doses of 0.25mg, 0.5mg, 1mg, Wegovy goes up to 1.7mg and 2.4mg (the maximum dose). The recommended starting dose for both medications is typically the lowest available dose, with the dosage gradually increased over time. However, you should always follow your doctors guidance around dosing.

Ozempic was approved by the FDA in 2017 for use in adults with type 2 diabetes, and later for use in adults without diabetes for weight loss. Wegovy, on the other hand, was only recently approved by the FDA in June 2021 specifically for weight loss in adults who are overweight or obese.

Both medications are given by injection, but they have different injection devices. Ozempic is administered once a week. Wegovy is administered once a week for the first month and then once every four weeks thereafter. 

Both medications can cause similar side effects as mentioned above. The severity and frequency of side effects can vary between individuals and may depend on the dosage.


There have been several types of weight loss injections that have been researched. Here’s a brief overview of the most popular ones:

Wegovy and Ozempic (Semaglutide) – This injectable medication is a GLP-1 agonist and has been found to be effective in clinical trials for weight loss. It is currently undergoing review by the FDA for approval for weight loss.

Saxenda (Liraglutide) – This is another GLP-1 drug, which regulates appetite and digestion. It has been approved by the FDA for use in adults with a BMI of 30 or greater or for those with a BMI of 27 or greater who also have at least one weight-related health condition, such as high blood pressure, type 2 diabetes, or high cholesterol.

Human chorionic gonadotropin (HCG) – This hormone is sometimes used in combination with a very low-calorie diet to promote weight loss. However, there is little evidence to support its effectiveness, and the FDA has not approved it yet for weight loss purposes.

B12 injections – While not specifically designed for weight loss, some people use vitamin B12 injections to boost their energy levels and metabolism, which can indirectly aid in weight loss efforts.


If you care about your body and want to lose weight safely and in a way that supports your wider health, think twice before getting a weight loss injection. These injections come with risks. Weight loss medications in general do not have a good safety record. One research paper found that 25 anti-obesity medications were withdrawn between 1964 and 2009 due to safety concerns.

Making changes to your diet and lifestyle can help you lose weight in a safe and sustainable way, with long-term results and no risks from drugs or surgeries. Working with a dedicated nutritionist means that you can benefit from tailored health, diet and lifestyle guidance along with supportive accountability.


If you’re looking for something to support your weight loss, you may wish to consider supplements. Of course, optimising your diet and lifestyle and exercising regularly comes first. However, certain quality supplements can support your efforts. Green tea extract and capsaicin supplements have been shown to speed up the metabolic rate. Glucomannan is a fibre supplement that swells in the stomach and can reduce appetite. CLA is a well researched dietary fat that works in various ways to support fat loss. You may wish to explore these naturally occurring compounds as an alternative to a fat burning injection. Read our article on evidence based weight loss supplements for more.


If you’re looking to lose weight, there really is no substitute for a holistic approach to weight loss. We can help you overcome your weight challenges, reach your ideal weight and maintain it long term. Book yourself in for a complimentary 25 mintue call or contact us and a member of our team will be in touch soon. We can talk through your challenges and explore whether one of our Intelligent Weight Loss programmes is right for you.



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Sarah has worked with hundreds of clients over the past decade to help them live in a healthy body that they feel confident in.

Sarah spent a large part of her teens and 20’s as a professional dancer battling with orthorexia and an unhealthy relationship with food and her body. This created a desire to understand the human body more so she could finally cut through the confusion and end the cycle of yoyo dieting. This fuelled her passion to help other women do the same.


Sarah specialises in supporting women who are struggling to lose weight due to underlying health issues. She’s helped many women manage their weight during and after the menopause, as well as clients with thyroid disease and immune system dysfunction. Sarah loves food and sharing healthy recipes with her clients. Her aim is to ensure that clients don’t feel deprived and instead, achieve their weight loss and health goals in a positive and sustainable way.


To enquire about working with Sarah, please contact us.



Ailsa is one of our most experienced practitioners. She specialises in helping clients to lose weight, develop a healthy relationship with food and finally feel comfortable in their skin. Ailsa’s mission is for everyone she works with to enjoy the journey and that working with a nutritionist should not be a punishment, but your access to a new possibility.


Ailsa is not only an experienced weight loss nutritionist, she is also a skilled coach. She helps our clients overcome emotional eating, destructive habits and self-sabotaging behaviours that have prevented successful weight loss in the past. Ailsa has spent years in clinic working with clients who have experienced yo-yo dieting and have discovered that long term weight loss is not just about eating less until you can stand it no longer.


Working with Ailsa you will be comprehensively supported, not only in improving your nutrition and lifestyle, but also your eating habits and your relationship with food. When you work on all these elements together, the results can be truly astonishing.


To enquire about working with Ailsa, please contact us.

Test Nikki is our Practice Manager, managing our team of practitioners and heading up the day-to-day running of the business. Nikki is involved in the strategic development of our practice, coming from a strong business background in town planning. A Florida girl, Nikki relocated to the UK in 2014 with her husband and two children.



Nikki is our Practice Manager, managing our team of practitioners and heading up the day-to-day running of th clinic.


Nikki is involved in the strategic development of our practice, coming from a strong business background in town planning.


A Florida girl, Nikki relocated to the UK in 2014 with her husband and two children.


Stéphanie is a skilled nutritional therapist and functional medicine practitioner with additional training in eating disorders, disordered eating and obesity. She believes that working towards both physiological and mental health is key in achieving optimum wellbeing.


Stéphanie’s personal experience of emotional eating and the ongoing struggle to find the right support led her to combine the science of nutrition with behavioural coaching to motivate and empower her clients. She specialises in helping people who struggle with their weight and their relationship with food. She helps them develop a healthier and more peaceful relationship with food and their bodies.


To enquire about working with Stéphanie, please contact us.


Inna is passionate about supporting women on their journey to improved health and wellbeing. She believes that the solution to effective weight loss does not lie in ever more restrictive diets, but a more sophisticated approach that optimises health and vitality, as well as promoting effective weight loss.


Working with Inna you will benefit from her in-depth knowledge of female health and hormones. She will support you in developing a healthy diet, lifestyle and mindset that ensures you reach your ideal weight and maintain it in the years to come.


Inna is passionate about food with a wide repertoire of delicious healthy recipes and meal ideas to ensure your weight loss journey is as enjoyable as possible!


To enquire about working with Inna, please contact us.



Ania is a firm believer that improving your health and losing weight should be a positive, empowering journey, not one centred around deprivation.


After being diagnosed with two autoimmune conditions in her twenties, Ania spent several years educating herself on the power of food and nutrition. She put it all into practise and changed her diet and lifestyle, reversing her endometriosis and thyroid disease. After experiencing such a significant improvement in her health, Ania had a big desire to help others. She embarked on a four year journey to study nutrition, graduating from the Institute for Optimum Nutrition with distinction.


Ania specialises in autoimmunity and works with clients who have underlying health issues preventing successful weight loss. Her expertise enables her to successfully support our clients with conditions such as hypothyroidsm (underactive thyroid), PCOS and diabetes. 


To enquire about working with Ania, please contact us.

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