
09 May What Weight Loss Drugs Are Available In The UK?
Weight loss drugs have gained significant attention in recent years as potential solutions to the growing obesity epidemic. However, far from an easy way to lose a couple of kgs before a holiday, these weight loss drugs are prescription medications that require medical oversight.
In the UK, a number of weight loss medications been approved for weight management. In this article we will explore the main weight loss drugs available in the UK, their licensing and prescription processes, and alternative approaches to weight loss.
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WHICH WEIGHT LOSS DRUGS ARE AVAILABLE IN THE UK?
The most prominent weight loss medications in the UK are injectable drugs that belong to the class of glucagon-like peptide-1 (GLP-1) receptor agonists. The following three are currently the most frequently prescribed versions. It’s important to remember that GLP-1 jabs come with concerning potential side effects. Your prescribing medical practitioner should talk you through the risks and ensure suitability before you start taking any medication for weight loss.
WEGOVY
Wegovy (semaglutide) is one of the most commonly prescribed drugs licensed for weight loss in the UK. Approved in the UK in September 2023, clinical trials have shown that people using Wegovy lost an average of 12% more of their body weight compared to placebo.
MOUNJARO
Mounjaro (tirzepatide) is a dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist. In December 2024 it was approved for treating obesity on the NHS and is available within specialist weight management services in England. It is expected to be made available via GPs starting from June 2025. In studies, patients experienced up to 22.5% weight loss.
SAXENDA
Saxenda (liraglutide) is another injectable option, taken once daily, which has been found to help people lose an average of 8% of their starting weight after 56 weeks.
WHAT OTHER WEIGHT LOSS DRUGS ARE THERE?
Globally, Ozempic has gained considerable popularity, particularly due to its use by celebrities like Elon Musk and Oprah Winfrey. Ozempic contains the same active ingredient as Wegovy (semaglutide) but in the UK, Ozempic is only licensed for use in type 2 diabetes. Its off-label use for weight loss has led to shortages, affecting patients who rely on it for diabetes treatment.
Other weight loss medications available in the UK include orlistat, sold under the brand names Xenical (prescription strength) and Alli (over-the-counter). Orlistat works preventing a portion of dietary fat from being absorbed into the body, which leads to reduced calorie intake.
CAN YOU GET WEIGHT LOSS DRUGS FROM PHARMACIES?
In May 2025, reports revealed that health officials are set to announce plans allowing weight loss injections to be made available ‘on prescription’ directly at pharmacies, following a short consultation. This will broaden access beyond specialist weight management clinics, potentially allowing people to obtain drugs like Ozempic and Mounjaro at a standard prescription charge (around £9.90), subject to eligibility and after a brief pharmacist-led assessment.
WEIGHT LOSS DRUGS ON THE NHS
In the UK, the licensing and prescription of weight loss drugs are, and should be, carefully regulated. Wegovy is available on the NHS as an option for weight management in line with NICE guidance. Patients are eligible for treatment within a specialist weight management service if they have at least one weight-related comorbidity and a BMI of at least 35, or a BMI of 30 to 34.9 if they meet the criteria for referral to specialist services. These medications are not available through general practitioners but require referral to a specialist weight management clinician. It’s important to note that weight loss drugs are intended to be used in conjunction with a healthy diet and physical activity. Mounjaro and Wegovy are also available for private purchase pending pharmacy approval.
WHO ARE WEIGHT LOSS DRUGS FOR?
While weight loss drugs may be effective tools for managing obesity, they are not suitable or necessary for everyone. To be eligible for treatment on the NHS, you need to have a BMI over 35 (or over 27.5 for individuals from certain ethnic minority backgrounds), and at least one weight-related health issue, such as diabetes, high blood pressure, or heart disease
We hear from many people who have tried weight loss medications but have discontinued due to intolerable side effects. Alternative approaches to weight loss, primarily diet and lifestyle optimisation, can be very effective when tailored to individual needs. These solutions come without the risks associated with GLP-1 use. Working with a qualified nutritionist can provide personalised guidance on health, nutrition and lifestyle strategies for effective weight management and facilitate long-term behaviour changes.
Bariatric surgery is offered by the NHS for those with severe obesity who have not succeeded with other methods. However, this is typically considered a last resort due to its invasive nature and potential risks. Read our guide to weight loss surgery to find out more about this treatment.
LEARN MORE ABOUT WEIGHT LOSS DRUGS
Read our other guides to weight loss injections to find out more.
- Do Weight Loss Injections Really Work?
- What Are The Side Effects?
- A Guide To Microdosing Ozempic
- How To Mimic Ozempic Without Drugs
- What To Eat When You’re Taking Weight Loss Drugs
WORK WITH US
For those who have long been struggling with their weight, weight loss drugs might feel like the quick fix they’ve been waiting for. However, they’re not without their risks or side effects, and for many, when the treatment stops, the weight returns.
We are a team of qualified, experienced weight loss nutritionists, who can help you make meaningful changes to your lifestyle and diet to ensure that you not only reach your desired weight, but maintain it long term.
We can help you overcome your weight challenges, reach your happy weight and maintain it long term. Book yourself in for a complimentary 25 mintue call or contact us and a member of our team will be in touch soon. We can talk through your challenges and explore whether one of our Intelligent Weight Loss programmes is right for you.
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